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Nutrient Deprivation Elicits a Transcriptional and Translational Inflammatory Response Coupled to Decreased Protein Synthesis

Nutrient deprivation inhibits mRNA translation through mTOR and eIF2α signaling, but it is unclear how the translational program is controlled to reflect the degree of a metabolic stress. In a model of breast cellular transformation, various forms of nutrient deprivation differentially affect the ra...

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Detalles Bibliográficos
Autores principales: Gameiro, Paulo A., Struhl, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419098/
https://www.ncbi.nlm.nih.gov/pubmed/30089253
http://dx.doi.org/10.1016/j.celrep.2018.07.021