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Polyplexes of Functional PAMAM Dendrimer/Apoptin Gene Induce Apoptosis of Human Primary Glioma Cells In Vitro

Highly efficient and safe gene delivery has become an important aspect of neuronal gene therapy. We evaluated the ability of polyamidoamine (PAMAM) dendrimer grafted with phenylalanine, histidine, and arginine (PAMAM-FHR), a nonviral gene delivery vector, to deliver a therapeutic, tumor cell-specifi...

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Detalles Bibliográficos
Autores principales: Bae, Yoonhee, Thuy, Le Thi, Lee, Young Hwa, Ko, Kyung Soo, Han, Jin, Choi, Joon Sig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419211/
https://www.ncbi.nlm.nih.gov/pubmed/30960280
http://dx.doi.org/10.3390/polym11020296