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Polyplexes of Functional PAMAM Dendrimer/Apoptin Gene Induce Apoptosis of Human Primary Glioma Cells In Vitro
Highly efficient and safe gene delivery has become an important aspect of neuronal gene therapy. We evaluated the ability of polyamidoamine (PAMAM) dendrimer grafted with phenylalanine, histidine, and arginine (PAMAM-FHR), a nonviral gene delivery vector, to deliver a therapeutic, tumor cell-specifi...
Autores principales: | Bae, Yoonhee, Thuy, Le Thi, Lee, Young Hwa, Ko, Kyung Soo, Han, Jin, Choi, Joon Sig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419211/ https://www.ncbi.nlm.nih.gov/pubmed/30960280 http://dx.doi.org/10.3390/polym11020296 |
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