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Genome-wide tracts of homozygosity and exome analyses reveal repetitive elements with Barrets esophagus/esophageal adenocarcinoma risk

BACKGROUND: Barrett’s esophagus (BE) is most commonly seen as the condition in which the normal squamous epithelium lining of the esophagus is replaced by goblet cells. Many studies show that BE is a predisposing factor for the development of esophageal adenocarcinoma (EAC), a particularly lethal ca...

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Detalles Bibliográficos
Autores principales: Wanchai, Visanu, Jin, Jing, Bircan, Emine, Eng, Charis, Orloff, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419328/
https://www.ncbi.nlm.nih.gov/pubmed/30871476
http://dx.doi.org/10.1186/s12859-019-2622-y