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Evaluation of linear models and missing value imputation for the analysis of peptide-centric proteomics

BACKGROUND: Several methods to handle data generated from bottom-up proteomics via liquid chromatography-mass spectrometry, particularly for peptide-centric quantification dealing with post-translational modification (PTM) analysis like reversible cysteine oxidation are evaluated. The paper proposes...

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Detalles Bibliográficos
Autores principales: Berg, Philip, McConnell, Evan W., Hicks, Leslie M., Popescu, Sorina C., Popescu, George V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419331/
https://www.ncbi.nlm.nih.gov/pubmed/30871482
http://dx.doi.org/10.1186/s12859-019-2619-6