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Evaluation of linear models and missing value imputation for the analysis of peptide-centric proteomics
BACKGROUND: Several methods to handle data generated from bottom-up proteomics via liquid chromatography-mass spectrometry, particularly for peptide-centric quantification dealing with post-translational modification (PTM) analysis like reversible cysteine oxidation are evaluated. The paper proposes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419331/ https://www.ncbi.nlm.nih.gov/pubmed/30871482 http://dx.doi.org/10.1186/s12859-019-2619-6 |