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Measuring inorganic phosphate and intracellular pH in the healthy and hypertrophic cardiomyopathy hearts by in vivo 7T (31)P-cardiovascular magnetic resonance spectroscopy

BACKGROUND: Cardiovascular phosphorus MR spectroscopy ((31)P-CMRS) is a powerful tool for probing energetics in the human heart, through quantification of phosphocreatine (PCr) to adenosine triphosphate (ATP) ratio. In principle, (31)P-CMRS can also measure cardiac intracellular pH (pH(i)) and the f...

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Detalles Bibliográficos
Autores principales: Valkovič, Ladislav, Clarke, William T., Schmid, Albrecht I., Raman, Betty, Ellis, Jane, Watkins, Hugh, Robson, Matthew D., Neubauer, Stefan, Rodgers, Christopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419336/
https://www.ncbi.nlm.nih.gov/pubmed/30871562
http://dx.doi.org/10.1186/s12968-019-0529-4