MiR-214 sensitizes human colon cancer cells to 5-FU by targeting Hsp27

Overcoming chemorestistance to 5-fluorouracil (5-FU) could offer a new treatment option for highly malignant colon cancer. In our study, differential microRNA expression profiling revealed that miR-214 is downregulated in 5-FU-resistant colon cancer cells compared to normal cells. In vitro, miR-214...

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Detalles Bibliográficos
Autores principales: Yang, Yong, Bao, Yan, Yang, Guo-Kai, Wan, Jia, Du, Ling-Juan, Ma, Zhen-Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419349/
https://www.ncbi.nlm.nih.gov/pubmed/30915129
http://dx.doi.org/10.1186/s11658-019-0143-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419349/
https://www.ncbi.nlm.nih.gov/pubmed/30915129
http://dx.doi.org/10.1186/s11658-019-0143-3

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