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Production of a cellular product consisting of monocytes stimulated with Sylatron(®) (Peginterferon alfa-2b) and Actimmune(®) (Interferon gamma-1b) for human use

BACKGROUND: Monocytes are myeloid cells that reside in the blood and bone marrow and respond to inflammation. At the site of inflammation, monocytes express cytokines and chemokines. Monocytes have been shown to be cytotoxic to tumor cells in the presence of pro-inflammatory cytokines such as Interf...

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Detalles Bibliográficos
Autores principales: Green, Daniel S., Nunes, Ana T., Tosh, Kevin W., David-Ocampo, Virginia, Fellowes, Vicki S., Ren, Jiaqiang, Jin, Jianjian, Frodigh, Sue-Ellen, Pham, Chauha, Procter, Jolynn, Tran, Celina, Ekwede, Irene, Khuu, Hanh, Stroncek, David F., Highfill, Steven L., Zoon, Kathryn C., Annunziata, Christina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419352/
https://www.ncbi.nlm.nih.gov/pubmed/30871636
http://dx.doi.org/10.1186/s12967-019-1822-6