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Production of a cellular product consisting of monocytes stimulated with Sylatron(®) (Peginterferon alfa-2b) and Actimmune(®) (Interferon gamma-1b) for human use
BACKGROUND: Monocytes are myeloid cells that reside in the blood and bone marrow and respond to inflammation. At the site of inflammation, monocytes express cytokines and chemokines. Monocytes have been shown to be cytotoxic to tumor cells in the presence of pro-inflammatory cytokines such as Interf...
Autores principales: | Green, Daniel S., Nunes, Ana T., Tosh, Kevin W., David-Ocampo, Virginia, Fellowes, Vicki S., Ren, Jiaqiang, Jin, Jianjian, Frodigh, Sue-Ellen, Pham, Chauha, Procter, Jolynn, Tran, Celina, Ekwede, Irene, Khuu, Hanh, Stroncek, David F., Highfill, Steven L., Zoon, Kathryn C., Annunziata, Christina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419352/ https://www.ncbi.nlm.nih.gov/pubmed/30871636 http://dx.doi.org/10.1186/s12967-019-1822-6 |
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