Cargando…
Human genes escaping X-inactivation revealed by single cell expression data
BACKGROUND: In mammals, sex chromosomes pose an inherent imbalance of gene expression between sexes. In each female somatic cell, random inactivation of one of the X-chromosomes restores this balance. While most genes from the inactivated X-chromosome are silenced, 15–25% are known to escape X-inact...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419355/ https://www.ncbi.nlm.nih.gov/pubmed/30871455 http://dx.doi.org/10.1186/s12864-019-5507-6 |