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Concurrent infections of dengue virus serotypes in Bali, Indonesia

OBJECTIVE: To describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia. RESULTS: During a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were...

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Autores principales: Masyeni, Sri, Yohan, Benediktus, Sasmono, R. Tedjo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419402/
https://www.ncbi.nlm.nih.gov/pubmed/30871630
http://dx.doi.org/10.1186/s13104-019-4164-9
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author Masyeni, Sri
Yohan, Benediktus
Sasmono, R. Tedjo
author_facet Masyeni, Sri
Yohan, Benediktus
Sasmono, R. Tedjo
author_sort Masyeni, Sri
collection PubMed
description OBJECTIVE: To describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia. RESULTS: During a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were positive by DENV RT-PCR in which eight patients (five local and three international travelers) detected as having concurrent infections by two different DENV serotypes. Among the eight patients, the common dengue symptoms diagnosed were fever, headache, and myalgia. Six cases (75%) were diagnosed with dengue fever (DF) while two cases (25%) manifested with bleeding and were diagnosed with dengue hemorrhagic fever (DHF) grade 1. The DENVs concurrent infections involved all four DENV serotypes known to be circulating in Bali. Although cases of DENV concurrent infections have been implicated with severe manifestation, we observed that most of concurrent infections cases in our study were of mild clinical manifestation, that may be related to the changing of DENV serotype predominance which is occurring in Bali, Indonesia.
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spelling pubmed-64194022019-03-27 Concurrent infections of dengue virus serotypes in Bali, Indonesia Masyeni, Sri Yohan, Benediktus Sasmono, R. Tedjo BMC Res Notes Research Note OBJECTIVE: To describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia. RESULTS: During a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were positive by DENV RT-PCR in which eight patients (five local and three international travelers) detected as having concurrent infections by two different DENV serotypes. Among the eight patients, the common dengue symptoms diagnosed were fever, headache, and myalgia. Six cases (75%) were diagnosed with dengue fever (DF) while two cases (25%) manifested with bleeding and were diagnosed with dengue hemorrhagic fever (DHF) grade 1. The DENVs concurrent infections involved all four DENV serotypes known to be circulating in Bali. Although cases of DENV concurrent infections have been implicated with severe manifestation, we observed that most of concurrent infections cases in our study were of mild clinical manifestation, that may be related to the changing of DENV serotype predominance which is occurring in Bali, Indonesia. BioMed Central 2019-03-12 /pmc/articles/PMC6419402/ /pubmed/30871630 http://dx.doi.org/10.1186/s13104-019-4164-9 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Masyeni, Sri
Yohan, Benediktus
Sasmono, R. Tedjo
Concurrent infections of dengue virus serotypes in Bali, Indonesia
title Concurrent infections of dengue virus serotypes in Bali, Indonesia
title_full Concurrent infections of dengue virus serotypes in Bali, Indonesia
title_fullStr Concurrent infections of dengue virus serotypes in Bali, Indonesia
title_full_unstemmed Concurrent infections of dengue virus serotypes in Bali, Indonesia
title_short Concurrent infections of dengue virus serotypes in Bali, Indonesia
title_sort concurrent infections of dengue virus serotypes in bali, indonesia
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419402/
https://www.ncbi.nlm.nih.gov/pubmed/30871630
http://dx.doi.org/10.1186/s13104-019-4164-9
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