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Concurrent infections of dengue virus serotypes in Bali, Indonesia
OBJECTIVE: To describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia. RESULTS: During a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419402/ https://www.ncbi.nlm.nih.gov/pubmed/30871630 http://dx.doi.org/10.1186/s13104-019-4164-9 |
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author | Masyeni, Sri Yohan, Benediktus Sasmono, R. Tedjo |
author_facet | Masyeni, Sri Yohan, Benediktus Sasmono, R. Tedjo |
author_sort | Masyeni, Sri |
collection | PubMed |
description | OBJECTIVE: To describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia. RESULTS: During a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were positive by DENV RT-PCR in which eight patients (five local and three international travelers) detected as having concurrent infections by two different DENV serotypes. Among the eight patients, the common dengue symptoms diagnosed were fever, headache, and myalgia. Six cases (75%) were diagnosed with dengue fever (DF) while two cases (25%) manifested with bleeding and were diagnosed with dengue hemorrhagic fever (DHF) grade 1. The DENVs concurrent infections involved all four DENV serotypes known to be circulating in Bali. Although cases of DENV concurrent infections have been implicated with severe manifestation, we observed that most of concurrent infections cases in our study were of mild clinical manifestation, that may be related to the changing of DENV serotype predominance which is occurring in Bali, Indonesia. |
format | Online Article Text |
id | pubmed-6419402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-64194022019-03-27 Concurrent infections of dengue virus serotypes in Bali, Indonesia Masyeni, Sri Yohan, Benediktus Sasmono, R. Tedjo BMC Res Notes Research Note OBJECTIVE: To describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia. RESULTS: During a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were positive by DENV RT-PCR in which eight patients (five local and three international travelers) detected as having concurrent infections by two different DENV serotypes. Among the eight patients, the common dengue symptoms diagnosed were fever, headache, and myalgia. Six cases (75%) were diagnosed with dengue fever (DF) while two cases (25%) manifested with bleeding and were diagnosed with dengue hemorrhagic fever (DHF) grade 1. The DENVs concurrent infections involved all four DENV serotypes known to be circulating in Bali. Although cases of DENV concurrent infections have been implicated with severe manifestation, we observed that most of concurrent infections cases in our study were of mild clinical manifestation, that may be related to the changing of DENV serotype predominance which is occurring in Bali, Indonesia. BioMed Central 2019-03-12 /pmc/articles/PMC6419402/ /pubmed/30871630 http://dx.doi.org/10.1186/s13104-019-4164-9 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Note Masyeni, Sri Yohan, Benediktus Sasmono, R. Tedjo Concurrent infections of dengue virus serotypes in Bali, Indonesia |
title | Concurrent infections of dengue virus serotypes in Bali, Indonesia |
title_full | Concurrent infections of dengue virus serotypes in Bali, Indonesia |
title_fullStr | Concurrent infections of dengue virus serotypes in Bali, Indonesia |
title_full_unstemmed | Concurrent infections of dengue virus serotypes in Bali, Indonesia |
title_short | Concurrent infections of dengue virus serotypes in Bali, Indonesia |
title_sort | concurrent infections of dengue virus serotypes in bali, indonesia |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419402/ https://www.ncbi.nlm.nih.gov/pubmed/30871630 http://dx.doi.org/10.1186/s13104-019-4164-9 |
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