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Persistence of chloroquine resistance alleles in malaria endemic countries: a systematic review of burden and risk factors
BACKGROUND: Chloroquine, a previous highly efficacious, easy to use and affordable anti-malarial agent was withdrawn from malaria endemic regions due to high levels of resistance. This review collated evidence from published-reviewed articles to establish prevalence of Pfcrt 76T and Pfmdr-1 86Y alle...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419488/ https://www.ncbi.nlm.nih.gov/pubmed/30871535 http://dx.doi.org/10.1186/s12936-019-2716-z |