Cargando…

Melatonin enhances TNF-α-mediated cervical cancer HeLa cells death via suppressing CaMKII/Parkin/mitophagy axis

BACKGROUND: Tumor necrosis factor-α (TNF-α) immunotherapy controls the progression of human cervical cancer. Here, we explored the detailed molecular mechanisms played by melatonin in human cervical cancer (HeLa cells) death in the presence of TNF-α injury, with a particular attention to the mitocho...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Qinghe, Wang, Wuliang, Cui, Jinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419493/
https://www.ncbi.nlm.nih.gov/pubmed/30923460
http://dx.doi.org/10.1186/s12935-019-0777-2