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Melatonin enhances TNF-α-mediated cervical cancer HeLa cells death via suppressing CaMKII/Parkin/mitophagy axis
BACKGROUND: Tumor necrosis factor-α (TNF-α) immunotherapy controls the progression of human cervical cancer. Here, we explored the detailed molecular mechanisms played by melatonin in human cervical cancer (HeLa cells) death in the presence of TNF-α injury, with a particular attention to the mitocho...
Autores principales: | Zhao, Qinghe, Wang, Wuliang, Cui, Jinquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419493/ https://www.ncbi.nlm.nih.gov/pubmed/30923460 http://dx.doi.org/10.1186/s12935-019-0777-2 |
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