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INC280 inhibits Wnt/β-catenin and EMT signaling pathways and its induce apoptosis in diffuse gastric cancer positive for c-MET amplification

OBJECTIVE: Gastric cancer is more open related to genetic predisposition. In our RNA sequencing study on gastric cancer patients, Runt-related transcription factor-3 (RUNX3) expression was significantly down-regulated in gastric cancer. We showed that decreased levels of RUNX3 are significantly asso...

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Detalles Bibliográficos
Autores principales: Sohn, Sung-Hwa, Kim, Bohyun, Sul, Hee Jung, Kim, Yoo Jin, Kim, Hyeong Su, Kim, Hongtae, Seo, Jong Bok, Koh, Youngho, Zang, Dae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419497/
https://www.ncbi.nlm.nih.gov/pubmed/30871613
http://dx.doi.org/10.1186/s13104-019-4163-x