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Dichloroacetic acid upregulates apoptosis of ovarian cancer cells by regulating mitochondrial function
BACKGROUND: Metabolic reprogramming is a characteristic of tumor cells and is considered a potential therapeutic target. Even under aerobic conditions, tumor cells use glycolysis to produce energy, a phenomenon called the “Warburg effect”. Pyruvate dehydrogenase kinase 1 (PDK1) is a key factor linki...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419601/ https://www.ncbi.nlm.nih.gov/pubmed/30881027 http://dx.doi.org/10.2147/OTT.S194329 |