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Epigenetic‐Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease

Multiple myeloma (MM) bone disease is characterized by the development of osteolytic lesions, which cause severe complications affecting the morbidity, mortality, and treatment of myeloma patients. Myeloma tumors seeded within the bone microenvironment promote hyperactivation of osteoclasts and supp...

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Detalles Bibliográficos
Autores principales: Adamik, Juraj, Roodman, G David, Galson, Deborah L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419609/
https://www.ncbi.nlm.nih.gov/pubmed/30918921
http://dx.doi.org/10.1002/jbm4.10183