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Epigenetic‐Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease
Multiple myeloma (MM) bone disease is characterized by the development of osteolytic lesions, which cause severe complications affecting the morbidity, mortality, and treatment of myeloma patients. Myeloma tumors seeded within the bone microenvironment promote hyperactivation of osteoclasts and supp...
Autores principales: | Adamik, Juraj, Roodman, G David, Galson, Deborah L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419609/ https://www.ncbi.nlm.nih.gov/pubmed/30918921 http://dx.doi.org/10.1002/jbm4.10183 |
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