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Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis
BACKGROUND: Kinins are short peptides with a wide range of proinflammatory properties that are generated from kininogens in the so-called kallikrein-kinin system. Kinins exert their biological activities through stimulation of two distinct receptor subtypes, the kinin or bradykinin B1 and B2 recepto...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419653/ https://www.ncbi.nlm.nih.gov/pubmed/30874974 http://dx.doi.org/10.1186/s40635-019-0228-3 |