RIPK1 inhibition attenuates experimental autoimmune arthritis via suppression of osteoclastogenesis

BACKGROUND: Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease characterized by upregulation of inflammatory cell death and osteoclastogenesis. Necrostatin (NST)-1s is a chemical inhibitor of receptor-interacting serine/threonine-protein kinase (RIPK)1, which plays a role in ne...

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Detalles Bibliográficos
Autores principales: Jhun, Jooyeon, Lee, Seung Hoon, Kim, Se-Young, Ryu, Jaeyoon, Kwon, Ji Ye, Na, Hyun Sik, Jung, KyoungAh, Moon, Su-Jin, Cho, Mi-La, Min, Jun-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419814/
https://www.ncbi.nlm.nih.gov/pubmed/30876479
http://dx.doi.org/10.1186/s12967-019-1809-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419814/
https://www.ncbi.nlm.nih.gov/pubmed/30876479
http://dx.doi.org/10.1186/s12967-019-1809-3

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