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Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte

BACKGROUND: It is confirmed that adipose-derived stem cells (ADSCs) transplantation effectively relieves kidney fibrosis and type 2 diabetes disease in mice. Currently, exosome from urine-derived stem cells (USCs) can protect type 1 diabetes-mediated kidney injury and attenuate podocyte damage in di...

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Detalles Bibliográficos
Autores principales: Jin, Juan, Shi, Yifen, Gong, Jianguang, Zhao, Li, Li, Yiwen, He, Qiang, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419838/
https://www.ncbi.nlm.nih.gov/pubmed/30876481
http://dx.doi.org/10.1186/s13287-019-1177-1