Cargando…

Megakaryocytic dysfunction in immune thrombocytopenia is linked to autophagy

Immune thrombocytopenic purpura (ITP) is a multifactorial autoimmune disease characterized by both increased platelet destruction and/or reduced platelet production. Even though they are detected in ≤ 50% of ITP patients, auto-antibodies play a pivotal role in the pathogenesis of ITP. Recent experim...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Rui-jie, Shan, Ning-ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419848/
https://www.ncbi.nlm.nih.gov/pubmed/30923461
http://dx.doi.org/10.1186/s12935-019-0779-0