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Megakaryocytic dysfunction in immune thrombocytopenia is linked to autophagy
Immune thrombocytopenic purpura (ITP) is a multifactorial autoimmune disease characterized by both increased platelet destruction and/or reduced platelet production. Even though they are detected in ≤ 50% of ITP patients, auto-antibodies play a pivotal role in the pathogenesis of ITP. Recent experim...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419848/ https://www.ncbi.nlm.nih.gov/pubmed/30923461 http://dx.doi.org/10.1186/s12935-019-0779-0 |