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Identification of coordinately regulated microRNA-gene networks that differ in baboons discordant for LDL-cholesterol

RATIONALE: Plasma low-density lipoprotein cholesterol (plasma LDL-C), vascular endothelial cells and peripheral blood mononuclear cells (PBMCs), particularly monocytes, play key roles in initiating atherosclerosis, the primary cause of cardiovascular disease (CVD). Although the mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Karere, Genesio M., Glenn, Jeremy P., Birnbaum, Shifra, Garcia, Roy, VandeBerg, John L., Cox, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420018/
https://www.ncbi.nlm.nih.gov/pubmed/30875406
http://dx.doi.org/10.1371/journal.pone.0213494