TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells

CD1d-restricted invariant natural killer T (iNKT) cells represent a heterogeneous population of lipid-reactive T cells that are involved in many immune responses, mediated through T-cell receptor (TCR)–dependent and/or independent activation. Although numerous microbial lipid antigens (Ags) have bee...

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Detalles Bibliográficos
Autores principales: Paget, Christophe, Deng, Shenglou, Soulard, Daphnée, Priestman, David A., Speca, Silvia, von Gerichten, Johanna, Speak, Anneliese O., Saroha, Ashish, Pewzner-Jung, Yael, Futerman, Anthony H., Mallevaey, Thierry, Faveeuw, Christelle, Gu, Xiaobo, Platt, Frances M., Sandhoff, Roger, Trottein, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420026/
https://www.ncbi.nlm.nih.gov/pubmed/30822302
http://dx.doi.org/10.1371/journal.pbio.3000169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420026/
https://www.ncbi.nlm.nih.gov/pubmed/30822302
http://dx.doi.org/10.1371/journal.pbio.3000169

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