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Binding to Nanopatterned Antigens is Dominated by the Spatial Tolerance of Antibodies

Although repetitive patterns of antigens are crucial for certain immune responses, an understanding of how antibodies bind and dynamically interact with various spatial arrangements of molecules is lacking. Hence, we introduce a new method where molecularly precise nanoscale patterns of antigens are...

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Detalles Bibliográficos
Autores principales: Shaw, Alan, Hoffecker, Ian T, Smyrlaki, Ioanna, Rosa, Joao, Grevys, Algridas, Bratlie, Diane, Sandlie, Inger, Michaelsen, Terje Enar, Andersen, Jan Terje, Högberg, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420075/
https://www.ncbi.nlm.nih.gov/pubmed/30643273
http://dx.doi.org/10.1038/s41565-018-0336-3