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Binding to Nanopatterned Antigens is Dominated by the Spatial Tolerance of Antibodies
Although repetitive patterns of antigens are crucial for certain immune responses, an understanding of how antibodies bind and dynamically interact with various spatial arrangements of molecules is lacking. Hence, we introduce a new method where molecularly precise nanoscale patterns of antigens are...
Autores principales: | Shaw, Alan, Hoffecker, Ian T, Smyrlaki, Ioanna, Rosa, Joao, Grevys, Algridas, Bratlie, Diane, Sandlie, Inger, Michaelsen, Terje Enar, Andersen, Jan Terje, Högberg, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420075/ https://www.ncbi.nlm.nih.gov/pubmed/30643273 http://dx.doi.org/10.1038/s41565-018-0336-3 |
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