Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin

PURPOSE: To explore the effects of hypoxic non-small-cell lung cancer (NSCLC)-derived exosomes on NSCLC resistance to cisplatin. MATERIALS AND METHODS: Exosomes were isolated by differential centrifugation and characterized by transmission electron microscope and Western blotting. Quantitative real-...

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Detalles Bibliográficos
Autores principales: Dong, Caijun, Liu, Xingwang, Wang, Huisheng, Li, Jutao, Dai, Lei, Li, Jun, Xu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420102/
https://www.ncbi.nlm.nih.gov/pubmed/30881046
http://dx.doi.org/10.2147/OTT.S186922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420102/
https://www.ncbi.nlm.nih.gov/pubmed/30881046
http://dx.doi.org/10.2147/OTT.S186922

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