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Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin
PURPOSE: To explore the effects of hypoxic non-small-cell lung cancer (NSCLC)-derived exosomes on NSCLC resistance to cisplatin. MATERIALS AND METHODS: Exosomes were isolated by differential centrifugation and characterized by transmission electron microscope and Western blotting. Quantitative real-...
Autores principales: | Dong, Caijun, Liu, Xingwang, Wang, Huisheng, Li, Jutao, Dai, Lei, Li, Jun, Xu, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420102/ https://www.ncbi.nlm.nih.gov/pubmed/30881046 http://dx.doi.org/10.2147/OTT.S186922 |
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