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The 1980s: d-AP5, LTP and a Decade of NMDA Receptor Discoveries

In the 1960s and 70s, biochemical and pharmacological evidence was pointing toward glutamate as a synaptic transmitter at a number of distinct receptor classes, known as NMDA and non-NMDA receptors. The field, however, lacked a potent and highly selective antagonist to block these putative postsynap...

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Detalles Bibliográficos
Autores principales: Lodge, D., Watkins, J. C., Bortolotto, Z. A., Jane, D. E., Volianskis, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420420/
https://www.ncbi.nlm.nih.gov/pubmed/30284673
http://dx.doi.org/10.1007/s11064-018-2640-6