Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress

Iron overload is associated with various pathological changes which contribute to heart failure. Here, we examined mechanisms via which iron alters cardiomyocyte insulin sensitivity. Treatment of primary adult and neonatal cardiomyocytes as well as H9c2 cells with iron decreased insulin sensitivity...

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Detalles Bibliográficos
Autores principales: Sung, Hye Kyoung, Song, Erfei, Jahng, James Won Suk, Pantopoulos, Kostas, Sweeney, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420583/
https://www.ncbi.nlm.nih.gov/pubmed/30874600
http://dx.doi.org/10.1038/s41598-019-41111-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420583/
https://www.ncbi.nlm.nih.gov/pubmed/30874600
http://dx.doi.org/10.1038/s41598-019-41111-6

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