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Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress
Iron overload is associated with various pathological changes which contribute to heart failure. Here, we examined mechanisms via which iron alters cardiomyocyte insulin sensitivity. Treatment of primary adult and neonatal cardiomyocytes as well as H9c2 cells with iron decreased insulin sensitivity...
Autores principales: | Sung, Hye Kyoung, Song, Erfei, Jahng, James Won Suk, Pantopoulos, Kostas, Sweeney, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420583/ https://www.ncbi.nlm.nih.gov/pubmed/30874600 http://dx.doi.org/10.1038/s41598-019-41111-6 |
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