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In vitro metabolic activation of vitamin D3 by using a multi-compartment microfluidic liver-kidney organ on chip platform

Organ-on-chip platforms provide models that allow the representation of human physiological processes in cell-based miniaturized systems. Potential pre-clinical applications include drug testing and toxicity studies. Here we describe the use of a multi-compartment micro-fluidic chip to recapitulate...

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Detalles Bibliográficos
Autores principales: Theobald, Jannick, Abu el Maaty, Mohamed A., Kusterer, Nico, Wetterauer, Bernhard, Wink, Michael, Cheng, Xinlai, Wölfl, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420623/
https://www.ncbi.nlm.nih.gov/pubmed/30874583
http://dx.doi.org/10.1038/s41598-019-40851-9