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Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice

Some strains of the protozoan parasite Toxoplasma gondii (such as RH) are virulent in laboratory mice because they are not restricted by the Immunity-Related GTPase (IRG) resistance system in these mouse strains. In some wild-derived Eurasian mice (such as CIM) on the other hand, polymorphic IRG pro...

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Detalles Bibliográficos
Autores principales: Murillo-León, Mateo, Müller, Urs B., Zimmermann, Ines, Singh, Shishir, Widdershooven, Pia, Campos, Cláudia, Alvarez, Catalina, Könen-Waisman, Stephanie, Lukes, Nahleen, Ruzsics, Zsolt, Howard, Jonathan C., Schwemmle, Martin, Steinfeldt, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420625/
https://www.ncbi.nlm.nih.gov/pubmed/30874554
http://dx.doi.org/10.1038/s41467-019-09200-2