Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements

Determining cell lineage and function is critical to understanding human physiology and pathology. Although advances in lineage tracing methods provide new insight into cell fate, defining cellular diversity at the mammalian level remains a challenge. Here, we develop a genome editing strategy using...

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Detalles Bibliográficos
Autores principales: Hwang, Byungjin, Lee, Wookjae, Yum, Soo-Young, Jeon, Yujin, Cho, Namjin, Jang, Goo, Bang, Duhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420643/
https://www.ncbi.nlm.nih.gov/pubmed/30874552
http://dx.doi.org/10.1038/s41467-019-09203-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420643/
https://www.ncbi.nlm.nih.gov/pubmed/30874552
http://dx.doi.org/10.1038/s41467-019-09203-z

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