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Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements
Determining cell lineage and function is critical to understanding human physiology and pathology. Although advances in lineage tracing methods provide new insight into cell fate, defining cellular diversity at the mammalian level remains a challenge. Here, we develop a genome editing strategy using...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420643/ https://www.ncbi.nlm.nih.gov/pubmed/30874552 http://dx.doi.org/10.1038/s41467-019-09203-z |