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Silencing of maternal hepatic glucocorticoid receptor is essential for normal fetal development in mice
Excessive or chronic stress can lead to a variety of diseases due to aberrant activation of the glucocorticoid receptor (GR), a ligand activated transcription factor. Pregnancy represents a particular window of sensitivity in which excessive stress can have adverse outcomes, particularly on the deve...
Autores principales: | Quinn, Matthew A., McCalla, Amy, He, Bo, Xu, Xiaojiang, Cidlowski, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420645/ https://www.ncbi.nlm.nih.gov/pubmed/30911679 http://dx.doi.org/10.1038/s42003-019-0344-3 |
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