HSP70 is a negative regulator of NLRP3 inflammasome activation

The NOD-leucine rich repeat and pyrin containing protein 3 (NLRP3) inflammasome is a multi-protein complex, aimed at producing IL-1β in response to danger signals which must be tightly regulated. Here we investigated the importance of the stress sensor, Heat Shock Protein 70 (HSP70) on NLRP3 inflamm...

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Detalles Bibliográficos
Autores principales: Martine, Pierre, Chevriaux, Angélique, Derangère, Valentin, Apetoh, Lionel, Garrido, Carmen, Ghiringhelli, François, Rébé, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420651/
https://www.ncbi.nlm.nih.gov/pubmed/30874540
http://dx.doi.org/10.1038/s41419-019-1491-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420651/
https://www.ncbi.nlm.nih.gov/pubmed/30874540
http://dx.doi.org/10.1038/s41419-019-1491-7

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