A transient window of hypothyroidism alters neural progenitor cells and results in abnormal brain development

Cortical heterotopias are clusters of ectopic neurons in the brain and are associated with neurodevelopmental disorders like epilepsy and learning disabilities. We have previously characterized the robust penetrance of a heterotopia in a rat model, induced by thyroid hormone (TH) disruption during g...

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Detalles Bibliográficos
Autores principales: O’Shaughnessy, Katherine L., Thomas, Susan E., Spring, Stephanie R., Ford, Jermaine L., Ford, Richard L., Gilbert, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420655/
https://www.ncbi.nlm.nih.gov/pubmed/30874585
http://dx.doi.org/10.1038/s41598-019-40249-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420655/
https://www.ncbi.nlm.nih.gov/pubmed/30874585
http://dx.doi.org/10.1038/s41598-019-40249-7

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