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A transient window of hypothyroidism alters neural progenitor cells and results in abnormal brain development
Cortical heterotopias are clusters of ectopic neurons in the brain and are associated with neurodevelopmental disorders like epilepsy and learning disabilities. We have previously characterized the robust penetrance of a heterotopia in a rat model, induced by thyroid hormone (TH) disruption during g...
Autores principales: | O’Shaughnessy, Katherine L., Thomas, Susan E., Spring, Stephanie R., Ford, Jermaine L., Ford, Richard L., Gilbert, Mary E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420655/ https://www.ncbi.nlm.nih.gov/pubmed/30874585 http://dx.doi.org/10.1038/s41598-019-40249-7 |
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