Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder

The major depressive disorder (MDD) working group of the Psychiatric Genomics Consortium (PGC) has published a genome-wide association study (GWAS) for MDD in 130,664 cases, identifying 44 risk variants. We used these results to investigate potential drug targets and repurposing opportunities. We bu...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaspar, Héléna A., Gerring, Zachary, Hübel, Christopher, Middeldorp, Christel M., Derks, Eske M., Breen, Gerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420656/
https://www.ncbi.nlm.nih.gov/pubmed/30877270
http://dx.doi.org/10.1038/s41398-019-0451-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420656/
https://www.ncbi.nlm.nih.gov/pubmed/30877270
http://dx.doi.org/10.1038/s41398-019-0451-4

Ejemplares similares