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Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder

The major depressive disorder (MDD) working group of the Psychiatric Genomics Consortium (PGC) has published a genome-wide association study (GWAS) for MDD in 130,664 cases, identifying 44 risk variants. We used these results to investigate potential drug targets and repurposing opportunities. We bu...

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Detalles Bibliográficos
Autores principales:	Gaspar, Héléna A., Gerring, Zachary, Hübel, Christopher, Middeldorp, Christel M., Derks, Eske M., Breen, Gerome
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420656/ https://www.ncbi.nlm.nih.gov/pubmed/30877270 http://dx.doi.org/10.1038/s41398-019-0451-4

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