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Gadd45b mediates depressive-like role through DNA demethylation

Animal studies using chronic social defeat stress (CSDS) in mice showed that brain-derived neurotrophic factor (BDNF) signaling in the mesolimbic dopamine (DA) circuit is important for the development of social aversion. However, the downstream molecular targets after BDNF release from ventral tegme...

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Detalles Bibliográficos
Autores principales: Labonté, Benoit, Jeong, Yun Ha, Parise, Eric, Issler, Orna, Fatma, Mena, Engmann, Olivia, Cho, Kyung-Ah, Neve, Rachael, Nestler, Eric J., Koo, Ja Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420662/
https://www.ncbi.nlm.nih.gov/pubmed/30874581
http://dx.doi.org/10.1038/s41598-019-40844-8