Sulforaphane metabolites inhibit migration and invasion via microtubule-mediated Claudins dysfunction or inhibition of autolysosome formation in human non-small cell lung cancer cells

Both sulforaphane-cysteine (SFN-Cys) and sulforaphane-N-acetyl-l-cysteine (SFN-NAC) inhibited cancer migration and invasion, but the underlying mechanisms were not clear. Here we uncovered via tissue microarray assay that high expression of invasion-associated Claudin-5 was correlated to malignant g...

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Detalles Bibliográficos
Autores principales: Zheng, Zhongnan, Lin, Kai, Hu, Yabin, Zhou, Yan, Ding, Xiaoyan, Wang, Yalin, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420664/
https://www.ncbi.nlm.nih.gov/pubmed/30874545
http://dx.doi.org/10.1038/s41419-019-1489-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420664/
https://www.ncbi.nlm.nih.gov/pubmed/30874545
http://dx.doi.org/10.1038/s41419-019-1489-1

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