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Sulforaphane metabolites inhibit migration and invasion via microtubule-mediated Claudins dysfunction or inhibition of autolysosome formation in human non-small cell lung cancer cells
Both sulforaphane-cysteine (SFN-Cys) and sulforaphane-N-acetyl-l-cysteine (SFN-NAC) inhibited cancer migration and invasion, but the underlying mechanisms were not clear. Here we uncovered via tissue microarray assay that high expression of invasion-associated Claudin-5 was correlated to malignant g...
Autores principales: | Zheng, Zhongnan, Lin, Kai, Hu, Yabin, Zhou, Yan, Ding, Xiaoyan, Wang, Yalin, Wu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420664/ https://www.ncbi.nlm.nih.gov/pubmed/30874545 http://dx.doi.org/10.1038/s41419-019-1489-1 |
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