ATG5-mediated autophagy suppresses NF-κB signaling to limit epithelial inflammatory response to kidney injury

G2/M-arrested proximal tubular epithelial cells (TECs) after renal injury are linked to increased cytokines production. ATG5-mediated autophagy in proximal TECs has recently been shown to protect against G2/M cell cycle arrest and renal fibrosis. However, the impacts of autophagy in regulating infla...

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Detalles Bibliográficos
Autores principales: Peng, Xuan, Wang, Yating, Li, Huiyan, Fan, Jinjin, Shen, Jiani, Yu, Xueqing, Zhou, Yi, Mao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420665/
https://www.ncbi.nlm.nih.gov/pubmed/30874544
http://dx.doi.org/10.1038/s41419-019-1483-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420665/
https://www.ncbi.nlm.nih.gov/pubmed/30874544
http://dx.doi.org/10.1038/s41419-019-1483-7

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