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ATG5-mediated autophagy suppresses NF-κB signaling to limit epithelial inflammatory response to kidney injury
G2/M-arrested proximal tubular epithelial cells (TECs) after renal injury are linked to increased cytokines production. ATG5-mediated autophagy in proximal TECs has recently been shown to protect against G2/M cell cycle arrest and renal fibrosis. However, the impacts of autophagy in regulating infla...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420665/ https://www.ncbi.nlm.nih.gov/pubmed/30874544 http://dx.doi.org/10.1038/s41419-019-1483-7 |