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The protective role of TBX21-1514T>C polymorphism in susceptibility to multiple sclerosis

Background: As a T-cell mediated disease, multiple sclerosis (MS) pathogenesis might be associated with the immune system and its involved genes. TBX21, which encodes T-bet transcription factor, is a critical regulator of the commitment to the Th1 lineage and Interferon gamma (IFNγ) production. Inve...

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Detalles Bibliográficos
Autores principales: Akbarian, Fatemeh, Ataei, Mitra, Salehi, Zivar, Nabavi, Masoud, Sanati, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420692/
https://www.ncbi.nlm.nih.gov/pubmed/30886677