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Molecular markers and potential therapeutic targets in non-WNT/non-SHH (group 3 and group 4) medulloblastomas

Childhood medulloblastomas (MB) are heterogeneous and are divided into four molecular subgroups. The provisional non-wingless-activated (WNT)/non-sonic hedgehog-activated (SHH) category combining group 3 and group 4 represents over two thirds of all MBs, coupled with the highest rates of metastases...

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Detalles Bibliográficos
Autores principales: Menyhárt, Otília, Giangaspero, Felice, Győrffy, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420757/
https://www.ncbi.nlm.nih.gov/pubmed/30876441
http://dx.doi.org/10.1186/s13045-019-0712-y